10.18170/DVN/NJIVQB Ruochen Dai(Central University of Finance and Economics)Zhongkun Zhu(Peking University)Xiaobo Zhang(Peking University) Peking University Open Research Data Platform 2021 Index of Regional Innovation and Entrepreneurship in China (IRIEC) is constructed by the Center for Enterprise Research (CER) of Peking University as an objective, real-time and multi-dimensional index to reflect the temporal and spatial distribution of innovation and entrepreneurship activities, utilizing administrative business enterprise registration database in China from 1990 to 2020 in combination with big data from other sources. We mainly focus on three core elements, i.e., entrepreneurship, capital, and technology, using the number of new enterprises, outside direct investment, venture capital investment, number of patents granted, and trademark registration.